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Human Clinical Trials A 12-week facial cream study enrolling 71 women with mild to advanced photoaging documented multiple improvements: increased skin density and thickness, reduced laxity, improved clarity, and reduced fine lines with decreased wrinkle depth

In test-tube studies, alpha-lipoic acid has reduced markers of inflammation, including NF-kB, ICAM-1, VCAM-1, MMP-2, MMP-9, and IL-6 ( May lower heart disease risk factors Heart disease is responsible for one in four deaths in America ( Research from a combination of lab, animal, and human studies has shown that the antioxidant properties of alpha-lipoic acid may lower several heart disease risk factors

However, the function of MGST3 in EMs remains unclear

62 At the same time, amino acid catabolism adapts to support GSH